Whom portrays Karen mother? What actor takes on the role of Karen Wheeler in the series? Whom is the performer behind Karen Wheeler? Mrs. Wheeler is brought to life by whom? Which actor plays the character of Karen Wheeler on the show? Whom is the talent bringing Karen Wheeler's character to life? Which actress takes on the role of Karen Wheeler in the television show? Who takes on the part of Karen Wheeler? Who is the talented individual portraying Karen the mother on the series? Which actor brings the character of Karen Wheeler to the screen?